The unbeaten 49ers host a Commanders side that has won once in five games. We back San Francisco to cover at home and build an SGM around Mike Evans.
The unbeaten Chiefs come off a bye to host a winless Chargers side. We expect a Kansas City win but think 7.5 points is a lot to give in a divisional game.
A rested, high-scoring Panthers side visit an Eagles defence giving up 400 yards a game. The winner is hard to pick, so we back the Over.
A 1-4 Saints side conceding 30 a game are favourites at MetLife, which looks wrong. We back the Giants at the line and add the Over in an SGM.
Drake Maye's Patriots should beat the Jets at home, but a strong Jets defence makes the 7.5-point line hard to call. We take New England head to head.
Week 6 starts at Mile High, with rain and wind forecast. We like Denver at home with the start and expect a low-scoring game between two struggling offences.
